Laboratory of Excellence HepSYS 
Functional genomics of viral hepatitis and liver disease
 

JOB OFFERS 

 Postdoctoral/ project leader position in host target discovery for hepatitis B virus cure

The laboratory of Thomas F. Baumert, MD at Inserm - the French National Institutes of Health and the University of Strasbourg focuses on the functional genomics of virus-host interactions and the discovery of novel targets for cure of viral infection and treatment of liver disease (Colpitts et al. Gut 2017, Verrier et al. Cell Rep. 2016, Crouchet et al. Gut 2016, Verrier et al. Hepatology 2016, Felmlee et al. Lancet Infect. Dis. 2016, Mailly et al. Nature Biotechnol.2015; Majzoub et al. Cell 2014; Chung & Baumert N. Engl. J. Med. 2014; Zona et al. Cell Host Microbe 2013; Fofana et al. Gastroenterology 2012; Lupberger, Zeisel et al. Nat. Med. 2011).

What we are looking for

We are looking for a highly motivated scientist (PhD or MD) with a strong background in virology, cell biology or genomics to lead and manage an EU-funded project on the discovery of host factors as targets for HBV cure. A solid track record of publications and excellent communication skills with English proficiency are desired. French is not a prerequisite. The position is available from October 1, 2017 (negotiable).

 What we offer

Aiming to discover of novel targets for hepatitis B virus cure,the scientist will apply cutting-edge technologies in functional genomics including genome-wide gain- and loss-of-function screens as well as single cell RNASeq profiling. We provide the opportunity to work in a stimulating, highly dynamic and international environment including strong collaborations with pharma. The unit is well funded including grants through the EU (ERC Advanced Grant, EU Infect ERA), the US National Institutes of Heath and industry. We offer a competitive remuneration package with strong benefits and excellent long-term career opportunities within the Inserm and University of Strasbourg tenure-track programs.

Please send your CV (including experience, publications and academic references) and a brief statement of research interests to: Prof. Thomas Baumert (unit head)Thomas.Baumert@unistra.fr and Dr. Catherine Schuster (deputy unit head): Catherine.Schuster@unistra.fr.

 

Junior group leader

The Inserm Unit U1110, Institute for Viral and Liver Diseaseand the Laboratory of Excellence HepSYS (Head: Prof. Thomas F. Baumert, MD), University of Strasbourg, France is recruiting a junior group leader with an excellent track record and research interest in the study of virus-host interactions.

The unit offers an ideal internationally renowned research environment for the career development and evolution of researchers. A key focus area of the unit is the molecular investigation of virus-host interactions and their relevance for disease biology. Core aims of the research unit are the investigation of the mechanisms of virus-induced inflammation and cancer and to develop novel preventive or therapeutic approaches.

Junior group leaders that join our unit will benefit from our state-of-the-art infrastructure of the unit and a world-class scientific environment at Inserm and the University of Strasbourg. Financial support is possible through the LabEx HEPSYS, Inserm ATIP-AVENIR and the IDEX university programs. Furthermore, the candidate will have the opportunity to participate in the Inserm and University of Strasbourg faculty tenure track programs.

To apply, please send your CV (including experience, publications and academic references) and a brief statement of research interests to: Prof. Thomas Baumert (Thomas.Baumert@unistra.fr) and Catherine Corbel (Catherine.Corbel@unistra.fr).

 

Post-doctoral positions in functional genomics of virus-host interactions

Two EU ERC-funded post-doctoral positions are open at the Inserm Institute for Viral and Liver Disease (Inserm U1110) and the Laboratory of Excellence HepSYS (Head: Prof. Thomas F. Baumert, MD) at the University of Strasbourg, France. The institute is located in a state-of-the-art infrastructure and an internationally renowned research environment with all tech platforms on campus. Inserm and the University of Strasbourg are consistently ranked among the leading research organisations.

The Baumert laboratory focuses on the functional genomics of virus-host interactions to discover and develop novel preventive and therapeutic strategies for viral infection and liver disease (Colpitts et al. Gut 2017, Verrier et al. Cell Rep. 2016, Fauvelle et al. Gastroenterology 2016, Nakagawa et al. Cancer Cell 2016, Mailly et al. Nature Biotechnol. 2015; Majzoub et al. Cell 2014; Chung & Baumert N. Engl. J. Med. 2014; Zona et al. Cell Host Microbe 2013; Lupberger, Zeisel et al. Nature Med. 2011).

What we offer

Aiming to discover the cell circuits driving virus-induced disease biology and cancer, the successful candidates will focus on functional genomics of virus-host cell interactions. One position is open to apply CRISPR-Cas9 loss-of-function screens to uncover virus-induced disease biology using a novel human cell-based model system. A second position is open to develop novel humanized mouse models for virus-induced disease and cancer using AAV-mediated gene transfer and single cell RNASeq. We provide the opportunity to work in a highly dynamic and international environment with top-level collaborations within academia and industry. Furthermore we offer a competitive remuneration package, mentoring and long-term career opportunities within the Inserm tenure track program for junior faculty.

Profile

You are a highly motivated PhD or MD with a strong background in cell biology, virology or functional genomics (position 1) or animal experimentation (position 2) and have a solid track record of publications. You have excellent communication skills in written and spoken English. French is not required.

To apply, please send your motivation letter (why you are interested in this position) and CV (including experience, key publications and 3 academic references) to Prof. Thomas Baumert (Thomas.Baumert@unistra.fr) as well as the institute’s project manager Dr. Olga Koutsopoulos (koutsopoulos@unistra.fr).

 

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